Antioxidant Activity and phytochemical composition of the leaves of Solanum guaraniticum A. St.-Hil.

نویسندگان

  • Marina Zadra
  • Mariana Piana
  • Thiele Faccim de Brum
  • Aline Augusti Boligon
  • Robson Borba de Freitas
  • Michel Mansur Machado
  • Sílvio Terra Stefanello
  • Félix Alexandre Antunes Soares
  • Margareth Linde Athayde
چکیده

Solanum guaraniticum is a shrub belonging to the Solanaceae family popularly known in Brazil as jurubeba or false-jurubeba. The aim of this study was to evaluate the antioxidant activity of crude extract and chloroform, ethyl acetate and n-butanol fractions from its leaves, verifying the ability to remove reactive species and identify and quantify phenolic compounds. The ethyl acetate fraction showed the highest amount of total polyphenols (546.57 ± 2.35 mg gallic acid equivalent/g) and the lowest IC(50) (9.11 ± 0.75 µg/mL) by the DPPH method. Furthermore, the chloroform fraction presented the highest content of flavonoids (75.73 ± 0.34 mg rutin equivalents/g), tannins (56.03 ± 0.68 mg catechin equivalents/g) and alkaloids (10.79 ± 0.06 mg/g). This fraction was effective in the scavenging of reactive species by 2',7'-dichlorofluorescein diacetate assay, in addition to completely reducing protein carbonyl content and reducing lipid peroxidation at basal levels even at low concentrations. Chlorogenic, caffeic and rosmarinic acids were identified and quantified by HPLC/DAD. These results show that S. guaraniticum is rich in phenolic compounds and has potential as an antioxidant.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Day time trend in the phytochemical constituents and antioxidant activity of Azadirachta indica leaves

Background & Aim:Medicinal plants have been of immense therapeutic values to many communities, some traditional folklore places emphasis on collecting plants during the day for medicinal purpose. This study examined the effect of collection time on the phytochemical composition and antioxidant activity of Azadirachta indica leaves. Experimental: ...

متن کامل

Antioxidant, Antibacterial, Cytotoxic, and Anti-Inflammatory Potential of the Leaves of Solanum lycocarpum A. St. Hil. (Solanaceae)

Ethanol extract and fractions obtained from leaves of Solanum lycocarpum were examined in order to determine their phenolic composition, antioxidant, antibacterial, anti-inflammatory, and cytotoxic potential. High performance liquid chromatography coupled with DAD analysis indicated that the flavonoids apigenin and kaempferol were the main phenolic compounds present in dichloromethane and ethyl...

متن کامل

Syzygium jambos and Solanum guaraniticum show similar antioxidant properties but induce different enzymatic activities in the brain of rats.

Syzygium jambos and Solanum guaraniticum are both employed in Brazil as medicinal plants, even though their potential toxicity is not well established and they are frequently misused. The aim of this study was investigate the effect of the aqueous leaf extracts of both plants on δ-aminolevulinate dehydratase (δ-ALA-D) and acetylcholinesterase (AChE) activities and the antioxidant action against...

متن کامل

Phytochemical investigations and antioxidant activity of Prosopis farcta from South Khorasan

Background and objectives: The aim of this study was the phytochemical screening and determining the total antioxidant activity of prosopis. farcta a plant native to South Khorasan. It has been mentioned as a cure for diarrhea, measles, diabetes and some other diseases in home remedies. Neuroprotective and relaxing effects, increasing HDL, decreasing LDL and accelerati...

متن کامل

Effects of Extraction Solvents on the Antioxidant and Phytochemical Activities of Manihot Esculenta Leaves

Background: Plants contain diverse phytochemicals with different solubility levels, depending on their molecular charges and polarity. This study was conducted to examine the effects of three extraction solvents in their pure and aqueous forms: absolute petroleum ether, acetone and ethanol on the phytochemical profile and antioxidant activities of Manihot esculenta leaves extracts. Methods: Th...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:
  • Molecules

دوره 17 11  شماره 

صفحات  -

تاریخ انتشار 2012